General · 9 November 2025
Melatonin Sleep Supplement Linked to Increased Heart Failure Risk in Long-Term Users

New research suggests adults taking melatonin supplements for over a year face a 90 percent higher risk of developing heart failure, with users three times more likely to require hospitalization and twice as likely to die from any cause. The study, analyzing health records of over 130,000 insomnia patients, challenges perceptions of melatonin as a harmless sleep aid, though researchers stress the findings cannot prove direct causation and more investigation is needed.
Reported by American Heart Association · How we write briefs
